MHC Class II Antibody (M5/114), Alexa Fluor™ 750, Novus Biologicals™

Rat Monoclonal Antibody

Supplier:  Novus Biologicals NBP221789AF750

Catalog No. NP221789A70

Description

MHC Class II Monoclonal specifically detects MHC Class II in Mouse, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: MHC Class II
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: HLA-DMA
• Immunogen: Activated C57BL/6 mouse spleen cells
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: M5/114
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
• Host Species: Rat
• Purification Method: Protein G purified
• Research Discipline: Adaptive Immunity, Asthma, B Cell Development and Differentiation Markers, Cell Biology, Diabetes Research, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators
• Gene ID (Entrez): 3108.0
• Target Species: Mouse, Rat
• Isotype: IgG2b