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I-Ab Mouse anti-Mouse, PE, Clone: 25-9-3, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen A14747

Catalog No. 50-113-6966


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Description

Description

MHC class II molecules are heterodimers of non-covalently associated alpha (31-34 kDa) and beta (26-29 kDa) chains. Major histocompatibility complex class II antigen presentation requires the participation of lysosomal proteases in two convergent processes. First, the antigens endocytosed by the antigen presenting cells must be broken down into antigenic peptides. Second, class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lymphocytes, which are usually T helper cells. CD4 interacts with non-polymorphic residues of MHC class II.
Specifications

Specifications

I-Ab, MHC Class II I-Ab
Monoclonal
0.1 mg/mL
PBS with 0.1% sodium azide
P06342
H-2 class II histocompatibility antigen A beta chain, H2-AB1, H2-iabeta
Mouse
IgM
25 μg
4° C
Primary
14961
Flow Cytometry
25-9-3
PE
H2-Ab1
Liquid
H2-Ab1
C3H.SW splenocytes.
Purified
RUO
Antibody
Monoclonal
Mouse
Documents
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