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MHC I polymorphic Monoclonal Antibody (ER-MP42), Invitrogen™

Catalog No. MA181746
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250 μg
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MA181746 250 μg
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Catalog No. MA181746 Supplier Thermo Scientific Supplier No. MA181746

Description

Rat Monoclonal Antibody

Clone ER-MP42 specifically recognizes mouse strains with the haplotypes H-2Kv, H-2Dd and H-2k, q, s. Mouse strains with the haplotypes H-2p, r, w7, w22 show weak reactivity with this antibody. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region. The polymorphic epitope is present on murine MHC class I molecules, which are expressed at varying levels on the majority of nucleated cells. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MHC I polymorphic
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone ER-MP42
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene H2-K1
Gene Accession No. P01895, P01896, P01897, P01899, P01900, P01901, P03991, P04223, P14426, P14427, P14428
Gene Alias blastocyst MHC; class I major histocompatibility antigen H-2Kd; H2 blastocyst; H-2 class I histocompatibility antigen, D-B alpha chain; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H2-B1; H2-Bl; H-2D; H2-D; H-2D cell surface glycoprotein; H-2D(B); H2-D1; H2-DC1-beta transplantation antigen protein; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, blastocyst; histocompatibility 2, D region locus 1; histocompatibility 2, K1, K region; K-f; MHC Class 1; MHC class I antigen; MHC class I antigen splice variant Bl.1; MHC class I H2 antigen; MHC class I H-2Dp; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-D-q alpha-chain; MHC H2-K transplantation antigen; Q5k protein
Gene Symbols H2-Bl, H2-D1, H2-K1
Host Species Rat
Immunogen Balb/c macrophage precursor cell hybrids.
Purification Method Protein G
Quantity 250 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14963, 14964, 14972
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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