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MIA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 157341AP

Catalog No. 50-173-0441


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Description

Description

Tumorigenesis is a process that is mediated by a network of membrane, cytosolic and nuclear associated factors, which regulate proliferation and cell-matrix interaction through signaling cascades. The phenotype of maligt melanomas in vivo depends on the global expression of stimulatory or inhibitory factors generated in both the tumors cells and their environment. One example, Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP), MIA) is a Src homology 3 (SH3)-like domain containing protein that is secreted from chondrocytes and maligt melanoma cells. MIA is translated as a 131-amino acid pro-form and processed into a mature 107-amino acid protein after cleavage of a secretion signal. MIA is expressed during chondrogenesis and in mature chondrocytes, suggesting that MIA is necessary for normal cartilage cell phenotype. MIA mRNA is present in carcinomas of the colon, ovary, kidney, and head/neck, and may represent a marker to monitor melanomic activity.
Specifications

Specifications

MIA
0.2 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q16674, Q61865, Q62946
CD RAP, Melanoma derived growth regulatory protein, melanoma inhibitory activity, MIA
Rabbit
IgG
150 μL
-20°C
Primary
12587, 81510, 8190
Immunohistochemistry (Paraffin)
Unconjugated
MIA
Liquid
Mia
MIA Fusion Protein Ag8499
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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