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Mib1/Mindbomb Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982201
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100 μL
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50-198-2201 100 μL
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Catalog No. 50-198-2201 Supplier Bioss Supplier No. BS12391R
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Description

Rabbit Polyclonal Antibody

MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.

Specifications

Antigen Mib1/Mindbomb
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MIB1
Gene Accession No. Q86YT6
Gene Alias DAPK-interacting protein 1; DAPK-interacting protein-1; Dip1; DIP-1; E3 ubiquitin-protein ligase MIB1; E430019M12Rik; Kiaa1323; LVNC7; Mib; MIB1; Mind bomb homolog 1; mind bomb-1; mindbomb E3 ubiquitin protein ligase 1; mindbomb homolog 1; mindbomb homolog 1 (Drosophila); mKIAA1323; RING-type E3 ubiquitin transferase MIB1; skeletrophin; ubiquitin ligase mind bomb; Zinc finger ZZ type with ankyrin repeat domain protein 2; ZZANK2; ZZZ6
Gene Symbols MIB1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Mib1/Mindbomb.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57534
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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