Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ MIB1 Monoclonal Antibody (2A7B1)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA531796
Description
MA5-31796 has been tested in indirect ELISA.
MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
Specifications
MIB1 | |
Monoclonal | |
1 mg/mL | |
PBS with 0.05% sodium azide | |
Q86YT6 | |
MIB1 | |
Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. coli. | |
100 μL | |
Primary | |
Human, Monkey | |
Antibody | |
IgG1 |
ELISA, Flow Cytometry, Western Blot | |
2A7B1 | |
Unconjugated | |
MIB1 | |
DAPK-interacting protein 1; DAPK-interacting protein-1; DIP1; DIP-1; E3 ubiquitin-protein ligase MIB1; E430019M12Rik; KIAA1323; LVNC7; MIB; MIB1; Mind bomb homolog 1; mind bomb-1; mindbomb E3 ubiquitin protein ligase 1; mindbomb homolog 1; mindbomb homolog 1 (Drosophila); mKIAA1323; RING-type E3 ubiquitin transferase MIB1; skeletrophin; ubiquitin ligase mind bomb; zinc finger ZZ type with ankyrin repeat domain protein 2; ZZANK2; ZZZ6 | |
Mouse | |
Protein G | |
RUO | |
57534 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction