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Invitrogen™ MIB1 Monoclonal Antibody (2A7B1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531796

Catalog No. PIMA531796


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Description

Description

MA5-31796 has been tested in indirect ELISA.

MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MIB1
Monoclonal
1 mg/mL
PBS with 0.05% sodium azide
Q86YT6
MIB1
Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. coli.
100 μL
Primary
Human, Monkey
Antibody
IgG1
ELISA, Flow Cytometry, Western Blot
2A7B1
Unconjugated
MIB1
DAPK-interacting protein 1; DAPK-interacting protein-1; DIP1; DIP-1; E3 ubiquitin-protein ligase MIB1; E430019M12Rik; KIAA1323; LVNC7; MIB; MIB1; Mind bomb homolog 1; mind bomb-1; mindbomb E3 ubiquitin protein ligase 1; mindbomb homolog 1; mindbomb homolog 1 (Drosophila); mKIAA1323; RING-type E3 ubiquitin transferase MIB1; skeletrophin; ubiquitin ligase mind bomb; zinc finger ZZ type with ankyrin repeat domain protein 2; ZZANK2; ZZZ6
Mouse
Protein G
RUO
57534
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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