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MIB1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501727541 Shop All Proteintech Group Inc Products
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150 μL
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50-172-7541 150 μL
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Catalog No. 50-172-7541 Supplier Proteintech Group Inc Supplier No. 118931AP150UL
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Description

Rabbit Polyclonal Antibody

MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.

Specifications

Antigen MIB1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene MIB1
Gene Accession No. Q86YT6
Gene Alias DAPK interacting protein 1, DIP 1, DIP1, KIAA1323, MIB, MIB1, Mind bomb homolog 1, ZZANK2, ZZZ6
Gene Symbols MIB1
Host Species Rabbit
Immunogen MIB1 Fusion Protein Ag2507
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57534
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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