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Invitrogen™ MICA Polyclonal Antibody
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Catalog No. PIPA535346
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400 μL
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PIPA535346 400 μL
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Catalog No. PIPA535346 Supplier Invitrogen™ Supplier No. PA535346
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Description

Rabbit Polyclonal Antibody

MICA Polyclonal Antibody for Western Blot, IHC (P), ICC/IF, Flow

Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. A related family, termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MICA
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene MICA
Gene Accession No. Q29983
Gene Alias DAMA-345G11.2; HLA class I antigen; MHC class I chain-related protein A; MHC class I polypeptide-related sequence A; MHC class I related sequence A; MICA; MIC-A; PERB11.1; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A
Gene Symbols MICA
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 68-97 amino acids from the central region of human MICA.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100507436
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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