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Invitrogen™ MICA Recombinant Rabbit Monoclonal Antibody (9F1)
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Catalog No. FEMA550167
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100 μL
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FEMA550167 100 μL
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Catalog No. FEMA550167 Supplier Invitrogen™ Supplier No. MA550167
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Rabbit Recombinant Monoclonal Antibody

MICA Recombinant Monoclonal Antibody for ELISA, IHC (P)

Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. A related family, termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.
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Specifications

Antigen MICA
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone 9F1
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.4
Gene MICA
Gene Accession No. Q29983
Gene Alias DAMA-345G11.2; HLA class I antigen; MHC class I chain-related protein A; MHC class I polypeptide-related sequence A; MHC class I related sequence A; MICA; MIC-A; PERB11.1; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A
Gene Symbols MICA
Host Species Rabbit
Immunogen A synthesized peptide derived from Human MICA.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100507436
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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