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Invitrogen™ MICAL2 Polyclonal Antibody
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Catalog No. PIPA556474
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100 μL
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PIPA556474 100 μL
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Catalog No. PIPA556474 Supplier Invitrogen™ Supplier No. PA556474
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PVTTGKEMAS AQEPDKLSMV MYLSKFYELF RGTPLRPVDS WRKNYGENAD LSLAKSSISN NYLNLTFPRK RTPRVDGQTG ENDMNKRRRK GFTNLDEPSN FSSRSLGSNQ ECGSSKEGGN QNKVKSM Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. There are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2. MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain and a Lin11, Isl-1 and Mec-3 (LIM) domain. It has been demonstrated that MICAL2 could regulate actin stress fibers and is required for normal actin organization. In addition, MICAL2-PV, a novel splicing variants of MICAL2, has been reported to be involved in cancer progression of prostate cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MICAL2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mical2
Gene Accession No. O94851
Gene Alias [F-actin]-monooxygenase MICAL2; 5330438E18Rik; 9530064J02; flavoprotein oxidoreductase MICAL2; Kiaa0750; Mical2; MICAL-2; MICAL2PV1; MICAL2PV2; microtubule associated monooxygenase, calponin and LIM domain containing 2; microtubule associated monoxygenase, calponin and LIM domain containing 2; mKIAA0750; mMical2; molecule interacting with CasL protein 2; protein MICAL-2; protein-methionine sulfoxide oxidase MICAL2; RGD1311773
Gene Symbols Mical2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MICAL2. Recombinant protein control fragment (Product #RP-88764).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9645
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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