Invitrogen™ MICB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566698

Catalog No. PIPA566698

Description

Immunogen sequence: CKKKTSAAEGP ELVSLQVLDQ HPVGTGDHRD AAQLGFQPLM SATGSTGSTE Highest antigen sequence identity to the following orthologs - mouse 33%, rat 33%.

MICB encodes the highly polymorphic MHC (HLA) class I chain-related gene B. The protein product is expressed on the cell surface. It is thought that MICB functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. MICB is broadly recognized by NK cells and T cells with NKG2D receptor on their surface. The complex NKG2D-MICB results in MICB expressing cytolytic T cells and NK cells against epithelial tumor cells.

Specifications

• Antigen: MICB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MICB
• Gene Alias: MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MHC class I-like located near the LRC, 2; MHC class I-like molecule PERB11.2-IMX; MHC I like leukocyte 2; MICB; MIC-B; Mill2; Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1; PERB11.2; sMICB; soluble MICB; stress inducible class I homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4277
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q29980
• Gene Symbols: MICB
• Immunogen: Recombinant Human MICB. Recombinant protein control fragment (Product #RP-107349).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov