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Invitrogen™ MID1 Polyclonal Antibody
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Catalog No. PIPA5109957
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100 μL
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PIPA5109957 100 μL
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Catalog No. PIPA5109957 Supplier Invitrogen™ Supplier No. PA5109957
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Description

Rabbit Polyclonal Antibody

MID1 Polyclonal Antibody for Western Blot, ICC/IF, ELISA

Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MID1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.06 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MID1
Gene Accession No. O15344, O70583
Gene Alias 61B3-R; BBBG1; DXHXS1141; E3 ubiquitin-protein ligase Midline-1; Finger on X and Y (in rat only on X); Fxy; GBBB1; Mid1; Midin; midline 1; midline 1 (Opitz/BBB syndrome); midline 1 RING finger protein; Midline1; midline-1; OGS1; Opitz/BBB syndrome; OS; OSX; Putative transcription factor XPRF; RING finger protein 59; RING finger protein Midline-1; RING-type E3 ubiquitin transferase Midline-1; RNF59; TRIM18; tripartite motif protein TRIM18; tripartite motif-containing protein 18; XPRF; zinc finger on X and Y, mouse, homolog of; ZNFXY
Gene Symbols MID1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17318, 4281
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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