Invitrogen™ MIER1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540896

Catalog No. PIPA540896

Description

Peptide sequence: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

Specifications

• Antigen: MIER1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MIER1
• Gene Alias: 4933425I22Rik; 5830411K19Rik; early response 1; er1; hMI-ER1; Kiaa1610; mesoderm induction early response 1 homolog; mesoderm induction early response 1 homolog (Xenopus laevis; mesoderm induction early response 1, transcriptional regulator; mesoderm induction early response protein 1; MIER1; MI-ER1; MIER1 transcriptional regulator; RGD1562337; RP5-944N15.1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 57708
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8N108
• Gene Symbols: MIER1
• Immunogen: Synthetic peptide directed towards the middle region of human MIER1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov