Invitrogen™ MIER1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565607

Catalog No. PIPA565607

Description

Immunogen sequence: GPTGGNKKPLH ADMDTNGYET DNLTTDPKLA HMTARNENDF DEKSERPAKR RRVNSNGKES PGSSEFFQEA VSHGKFEELE NTDD Highest antigen sequence identity to the following orthologs - mouse 89%, rat 87%.

The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

Specifications

• Antigen: MIER1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MIER1
• Gene Alias: 4933425I22Rik; 5830411K19Rik; early response 1; er1; hMI-ER1; Kiaa1610; mesoderm induction early response 1 homolog; mesoderm induction early response 1 homolog (Xenopus laevis; mesoderm induction early response 1, transcriptional regulator; mesoderm induction early response protein 1; MIER1; MI-ER1; MIER1 transcriptional regulator; RGD1562337; RP5-944N15.1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57708
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N108
• Gene Symbols: MIER1
• Immunogen: Recombinant Human MIER1. Recombinant protein control fragment (Product #RP-106272).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov