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Invitrogen™ MIF Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA128840
Description
PA1-28840 detects MIF from mouse, rat samples.
MIF (macrophage migration inhibitory factor) was one of the first cytokine activities to be discovered and was initially described as a T cell-derived factor that inhibits the random migration of macrophages (Weiser 1989). Recently, MIF was rediscovered as a pituitary hormone that act as the counterregulatory hormone for glucocorticoid action within the immune system (Bernhagen 1993, Mitchell 1995). MIF was released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production (Bucala 1998). MIF plays a critical role in the host control of inflammation and immunity.
Specifications
MIF | |
Polyclonal | |
Unconjugated | |
Mif | |
cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase | |
Rabbit | |
Protein A | |
RUO | |
17319, 81683 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunoprecipitation, Neutralization, Western Blot | |
1 mg/mL | |
PBS with 0.1% sodium azide; pH 7.2 | |
P30904, P34884 | |
Mif | |
Recombinant protein - full length rat MIF protein. | |
50 μg | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
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