Invitrogen™ MIF Recombinant Rabbit Monoclonal Antibody (BLR141J)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA544469

Catalog No. PIMA544469

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

MIF (macrophage migration inhibitory factor) was one of the first cytokine activities to be discovered and was initially described as a T cell-derived factor that inhibits the random migration of macrophages (Weiser 1989). Recently, MIF was rediscovered as a pituitary hormone that act as the counterregulatory hormone for glucocorticoid action within the immune system (Bernhagen 1993, Mitchell 1995). MIF was released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production (Bucala 1998). MIF plays a critical role in the host control of inflammation and immunity.

Specifications

• Antigen: MIF
• Classification: Recombinant Monoclonal
• Concentration: 50 μg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
• Gene Accession No.: P14174
• Gene Symbols: Mif
• Immunogen: Recombinant protein representing Human Macrophage migration inhibitory factor (residues 2-115).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: BLR141J
• Conjugate: Unconjugated
• Gene: Mif
• Gene Alias: cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase
• Host Species: Rabbit
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 4282
• Content And Storage: 4°C
• Form: Liquid