Invitrogen™ Mimecan Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547424

Catalog No. PIPA547424

Description

In direct ELISAs, approximately 10% cross-reactivity with recombinant human Mimecan is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.

Specifications

• Antigen: Mimecan
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OGN
• Gene Alias: 3110079A16Rik; corneal keratan sulfate proteoglycan; mimecan; mimecan proteoglycan; mimican; OG; Ogn; OIF; Osteoglycin; osteoglycin/mimecan; osteoinductive factor; SLRR3A
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18295
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q62000
• Gene Symbols: OGN
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Mimecan Ala20-Phe298.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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