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MINA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501727800 Shop All Proteintech Group Inc Products
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50-172-7800 150 μL
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Catalog No. 50-172-7800 Supplier Proteintech Group Inc Supplier No. 122141AP150UL
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Rabbit Polyclonal Antibody

MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.

Specifications

Antigen MINA
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RIOX2
Gene Accession No. Q8CD15, Q8CFC1, Q8IUF8
Gene Alias MDIG, MINA, Mina53, MYC induced nuclear antigen, NO52, Nucleolar protein 52
Gene Symbols RIOX2
Host Species Rabbit
Immunogen MINA Fusion Protein Ag2838
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 266670, 67014, 84864
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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