MIP-3 alpha Monoclonal Antibody (4N5F7), Rockland™

Rat Monoclonal Antibody

Supplier:  Rockland Immunochemicals 210501B51

Catalog No. 50-199-1507

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for mouse MIP-3 alpha protein. A BLAST analysis was used to suggest cross-reactivity with MIP-3 alpha from mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with MIP-3 alpha from other sources has not been determined.

Macrophage Inflammatory Protein-3 alpha (MIP-3alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells.

Specifications

• Antigen: MIP-3 alpha
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: O89093
• Gene Symbols: CCL20
• Immunogen: Anti-MIP-3alpha (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse MIP-3alpha produced in E.coli followed by hybridoma development.
• Regulatory Status: RUO
• Gene ID (Entrez): 20297
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Clone: 4N5F7
• Conjugate: Unconjugated
• Gene: CCL20
• Gene Alias: beta chemokine exodus-1; Beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; Larc; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 a; MIP 3alpha; MIP 3a; MIP3 a; MIP3 alpha; MIP3 a; MIP-3[a]; MIP3A; MIP-3a; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; Small-inducible cytokine A20; St38
• Host Species: Rat
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG