Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Tocris Miro1 Reducer

Promotes mitochondrial Rho GTPase 1 (Miro1) degradation

Manufacturer:  Tocris 7091/50

 View more versions of this product

Catalog No. 70-915-0


Add to cart
This item is not returnable. View return policy

Description

Description

Miro1 Reducer is a promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1). Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM). Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.
Specifications

Specifications

C20H16FN7O.HCl
Rhot1
50 mg
0.98
N-(3-Fluorophenyl)-N'-[4-[[6-(1 H-imidazol-1-yl)-4-pyrimidinyl]amino]phenyl]urea hydrochloride
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
Documents
Product Certifications
Promotions

Promotions

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit