Invitrogen™ Mist1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114474

Catalog No. PIPA5114474

Description

Positive controls that may be used include: Rat Small Intestine Tissue Lysate, Human Small Intestine Tissue Slide.

Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.

Specifications

• Antigen: Mist1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bhlha15
• Gene Alias: 1810009C13Rik; basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family member a15; basic helix-loop-helix family, member a15; Basic helix-loop-helix transcription factor (bHlH); bHlH; BHLHA15; BHLHB8; Class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST1; MIST-1; Muscle, intestine and stomach expression 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 168620, 17341, 25334
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P70562, Q7RTS1, Q9QYC3
• Gene Symbols: Bhlha15
• Immunogen: BHLHA15 antibody was raised against a 18 amino acid peptide near the center of human BHLHA15. The immunogen is located within amino acids 60 - 110 of BHLHA15.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG