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Invitrogen™ MiTF Monoclonal Antibody (1607CT834.207.47)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA537695
Description
MiTF Monoclonal Antibody for Western Blot, IHC (P)
Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells and bone development. The mutation of Mi causes Waardenburg Syndrome type II in humans. In mice, a profound loss of pigmented cells in the skin eye and inner ear results, as well as osteopetrosis and defects in natural killer and mast cells. There are two known isoforms of Mi differing by 66 amino acids at the NH2 terminus. Shorter forms are expressed in melanocytes and run as two bands at 52 kDa and 56 kDa, while the longer Mi form runs as a cluster of bands at 60-70 kDa in osteoclasts and in B16 melonoma cells (but not other melanoma cell lines), as well as mast cells and heart.
Specifications
MiTF | |
Monoclonal | |
0.35 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
O75030, O88368, Q08874 | |
MITF | |
recombinant protein of human MITF. | |
200 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG1 κ |
Immunohistochemistry (Paraffin), Western Blot | |
1607CT834.207.47 | |
Unconjugated | |
MITF | |
BCC2; Bhlhe32; black eyed white; bw; Class E basic helix-loop-helix protein 32; CMM8; Gsfbcc2; melanocyte inducing transcription factor; melanogenesis associated transcription factor; mi; microphtalmia-associated transcription factor; microphthalmia; microphthalmia associated transcription factor isoform M-; microphthalmia transcription factor; microphthalmia-associated transcription factor; microphthalmia-associated transcription factor A; microphthalmia-associated transcription factor isoform H; microphthalmia-associated transcription factor isoform H protein; microphthalmia-associated transcription factor Trnc-1; microphthalmia-associated transcription factor Trnc-2; microphthalmia-associated transcription factor variant 1; microphthalmia-associated transcription factor variant 2; microphthalmia-associated transcription factor variant 3; microphthalmia-associated transcription factor variant MITF-M(+); MITF; MITF-H; MITF-M; MITF-M-; transcription factor, isoform 7; vit; Vitiligo; Wh; WS2; WS2A | |
Mouse | |
Protein G | |
RUO | |
17342, 25094, 4286 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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