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Invitrogen™ Mitofilin Monoclonal Antibody (2E4AD5)
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Catalog No. 456400
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Catalog No. Quantity
45-640-0 100 μg
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Catalog No. 45-640-0 Supplier Invitrogen™ Supplier No. 456400
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Description

Mouse Monoclonal Antibody

Positive controls: Human fibroblasts; Human cerebellum tissue; Isolated mitochondria from Human, Bovine, Rat and Mouse hearts, HepG2 lysate; HL60 cells. This clone can also be referred to as clone number MM#7A-2E4AD5.

Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mitofilin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2E4AD5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation HEPES buffered saline with 0.02% sodium azide
Gene IMMT
Gene Accession No. Q16891, Q3KR86, Q8CAQ8
Gene Alias 1700082C19Rik; cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; D830041H16Rik; EMBL:AAI05842.1, ECO:0000312; EMBL:AAI05842.1}; HMP; Immt; immt {ECO:0000312; IMMT antibody; inner membrane mitochondrial protein; inner membrane protein, mitochondrial; inner membrane protein, mitochondrial (mitofilin); MGC133830 protein; MIC60; MICOS complex subunit Mic60; MINOS2; mitochondrial inner membrane organizing system 2; mitochondrial inner membrane protein; mitochondrial inner membrane protein {ECO:0000250; Mitofilin; mitofilin {ECO:0000250; motor protein; P87; p87/89; p87/89 antibody; P89; PIG4; PIG52; proliferation-inducing gene 4; RGD:1310684}; UniProtKB:Q8CAQ8, ECO:0000312; UniProtKB:Q8CAQ8}
Gene Symbols IMMT
Host Species Mouse
Immunogen Human heart mitochondria.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10989, 312444, 508853, 76614
Target Species Human, Mouse, Rat, Bovine
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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