Invitrogen™ Mitofilin Polyclonal Antibody

Catalog No.	Quantity
PIPA589627	100 μL

Catalog No. PIPA589627 Supplier Invitrogen™ Supplier No. PA589627

Description

Rabbit Polyclonal Antibody

Positive Samples: SW480, SW620, H460, HepG2, Mouse spleen, Mouse testis; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Single-pass membrane protein Immunogen sequence: EELEKMKSVI ENAKKKEVAG AKPHITAAEG KLHNMIVDLD NVVKKVQAAQ SEAKVVSQYH ELVVQARDDF KRELDSITPE VLPGWKGMSV SDLADKLSTD D.

Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.

Specifications

• Antigen: Mitofilin
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.64 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: IMMT
• Gene Accession No.: Q16891, Q3KR86, Q8CAQ8
• Gene Alias: 1700082C19Rik; cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; D830041H16Rik; EMBL:AAI05842.1, ECO:0000312; EMBL:AAI05842.1}; HMP; Immt; immt {ECO:0000312; IMMT antibody; inner membrane mitochondrial protein; inner membrane protein, mitochondrial; inner membrane protein, mitochondrial (mitofilin); MGC133830 protein; MIC60; MICOS complex subunit Mic60; MINOS2; mitochondrial inner membrane organizing system 2; mitochondrial inner membrane protein; mitochondrial inner membrane protein {ECO:0000250; Mitofilin; mitofilin {ECO:0000250; motor protein; P87; p87/89; p87/89 antibody; P89; PIG4; PIG52; proliferation-inducing gene 4; RGD:1310684}; UniProtKB:Q8CAQ8, ECO:0000312; UniProtKB:Q8CAQ8}
• Gene Symbols: IMMT
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human IMMT (NP_0068302).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10989, 312444, 76614
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov