Invitrogen™ Mitofilin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596203

Catalog No. PIPA596203

Description

Immunogen sequence: ESKQPASQLQ KQKGDTPASA TAPTEAAQII SAAGDTLSVP APAVQPEESL KTDHPEIGEG KPTPALSEEA SSSSIRERPP EEVAARLAQQ EKQEQVKIES LAKSLEDALR QTASVTLQAI AAQNAAVQAV NAHSNILKAA MDNSEIAGEK K; Positive Samples: MCF7, B cells, HeLa, HepG2, SH-SY5Y, HL-60, Mouse kidney; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Single-pass membrane protein.

Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.

Specifications

• Antigen: Mitofilin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IMMT
• Gene Alias: 1700082C19Rik; cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; D830041H16Rik; EMBL:AAI05842.1, ECO:0000312; EMBL:AAI05842.1}; HMP; Immt; immt {ECO:0000312; IMMT antibody; inner membrane mitochondrial protein; inner membrane protein, mitochondrial; inner membrane protein, mitochondrial (mitofilin); MGC133830 protein; MIC60; MICOS complex subunit Mic60; MINOS2; mitochondrial inner membrane organizing system 2; mitochondrial inner membrane protein; mitochondrial inner membrane protein {ECO:0000250; Mitofilin; mitofilin {ECO:0000250; motor protein; P87; p87/89; p87/89 antibody; P89; PIG4; PIG52; proliferation-inducing gene 4; RGD:1310684}; UniProtKB:Q8CAQ8, ECO:0000312; UniProtKB:Q8CAQ8}
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10989, 76614
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q16891, Q8CAQ8
• Gene Symbols: IMMT
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-270 of human IMMT (NP_0068302).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov