Mitomycin C, MP Biomedicals™

Description

The most widely used Mitomycin antibiotic. Mitomycin C, MP Biomedicals is the least toxic of the mitomycin antibiotics, with the most potent antitumor activity. It is an inhibitor of DNA synthesis, nuclear division, and cancer cells.

• Antibacterial to gram positive, gram negative and acid-fast bacilli
• Decomposes DNA in cancer cells by forming a complex with DNA
• Inhibits division of cancer cells by interfering with the biosynthesis of DNA

Specifications

Chemical Identifiers

• CAS: 50-07-7
• Molecular Formula: C15H18N4O5
• Molecular Weight (g/mol): 334.332
• InChI Key: NWIBSHFKIJFRCO-WUDYKRTCSA-N
• Synonym: Ametycin, 7-Amino-9-a-methoxymitosane, Mit-C, Mitocin-C, Mitomycinum, Mutamycin, Azirizino[2', 3': 3,4] pyrrolo [1,2-a] indole 4,7-dione-6-amino-1,1a, 2, 8, 8a, 8b-hexahydro- 8- (hydroxymethyl) 8a-methoxy-5-methyl carbamate
• PubChem CID: 5746
• ChEBI: CHEBI:27504
• SMILES: CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N

• Physical Form: Powder
• pH: 6 to 9 (Stability)
• Extinction Coefficient: EmM(367 nm) = 21.84 (water); EmM(357 nm) = 22.78 (methanol); E1% (216 nm) = 742 (methanol); E1% (360 nm) = 742 (methanol); E1% (560 nm) = 0.06 (methanol) (Lit.)
• Potency: 850μg/mg minimum
• Quantity: 2 mg
• Solubility Information: Soluble in dilute aqueous acids or dilute aqueous bases.
• Formula Weight: 334.33
• Grade: Antibiotic

Safety and Handling

Recommended Storage

Store at +4°C.

WARNING: Cancer - www.P65Warnings.ca.gov