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  5. Tocris Bioscience™ MK 0677

Tocris Bioscience™ MK 0677
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Catalog No. 527250
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Catalog No. Quantity
52-725-0 50 mg
52-721-0 10 mg
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Catalog No. 52-725-0 Supplier Tocris Bioscience™ Supplier No. 5272/50
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Description

High affinity ghrelin receptor agonist

MK 0677 is a high affinity ghrelin receptor agonist (pKi = 8.14). Growth hormone (GH) secretagog; stimulates GH release from rat pituitary cells in vitro (EC50 = 1.3 nM) and enhances GH plasma levels in vivo. Also attenuates isoproterenol -induced lipolysis in rat adipocytes in vitro. Orally bioavailable.

Specifications

Chemical Name or Material 2-Amino-N-[(1 R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3 H-indole-3,4 '-piperidin]-1 '-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate
CAS 159752-10-0
Synonym Ibutamoren mesylate, L-163,191
Quantity 50 mg
Target Ghrelin Receptor Agonists
Molecular Formula C27H36N4O5S.CH3SO3H
Formula Weight 624.77
Purity 98%
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