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Tocris Bioscience™ MK 386
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Catalog No. 58421
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Catalog No. Quantity
58-421 1 mg
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Catalog No. 58-421 Supplier Tocris Bioscience™ Supplier No. 5842/1
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Description

Potent, selective human type 1 5α-reductase inhibitor

Potent and selective human type 1 5α-reductase inhibitor (5αR1, IC50 = 0.9 nM). Exhibits 100-fold selectivity for 5αR1 over 5αR2 (IC50 = 154 nM). Supresses human serum and sebum dihydrotestosterone (DHT) levels in a dose-dependent manner without affecting semen DHT concentrations. Orally active.

Chemical Identifiers

CAS 158493-17-5
Molecular Formula C28H49NO

Specifications

Quantity 1 mg
Solubility Soluble to 100mM in DMSO
Formula Weight 415.69
Physical Form Oil
Purity >98%
Molecular Weight (g/mol) 415.706
Chemical Name or Material (4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H-

Safety and Handling

Recommended Storage Store at -20°C
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