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  5. Tocris Bioscience™ (+)-MK 801 maleate

Tocris Bioscience™ (+)-MK 801 maleate
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Catalog No. 092450
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50 mg
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Catalog No. Quantity
09-245-0 50 mg
09-241-0 10 mg
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Catalog No. 09-245-0 Supplier Tocris Bioscience™ Supplier No. 0924/50
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Description

Non-competitive NMDA antagonist; acts at ion channel site

(+)-MK 801 maleate is a high affinity (Ki = 37.2 nM), selective and non-competitive NMDA receptor antagonist. (+)-MK 801 maleate acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux. It is an effective anti-ischemic agent in several animal models. (+)-MK 801 maleate increases motor activity in rat models. (+)-MK 801 maleate inhibits proliferation and increases apoptosis in hippocampal neural stem cells (NSCs). (+)-MK 801 maleate induces schizophrenia-like symptoms in rodents.

(-)-enantiomer also available.

Chemical Identifiers

CAS 77086-22-7
Molecular Formula C20H19NO4

Specifications

Quantity 50 mg
Formula Weight 337.37
Purity >99%
Molecular Weight (g/mol) 337.375
Chemical Name or Material (+)-MK 801 maleate

Safety and Handling

Recommended Storage Store at Room Temperature
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