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Invitrogen™ MKL1 Monoclonal Antibody (CL4281)
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Catalog No. PIMA531399
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100 μL
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Catalog No. Quantity
PIMA531399 100 μL
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Catalog No. PIMA531399 Supplier Invitrogen™ Supplier No. MA531399
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Description

Mouse Monoclonal Antibody

Immunogen sequence: EQEKRAQQPA PAPAPLGTPV KQENSFSSCQ LSQQPLGPAH PFNPSLAAPA TNHIDPCAVA PGPPSVVVKQ EALQPEPEPV PAPQLLLGPQ GPSLIKGVAP PTLITDSTGT HLVLTVTNKN ADSPG Highest antigen sequence indentity to the following orthologs: Rat - 66%, Mouse - 65%.

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL4281
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mrtfa
Gene Accession No. Q969V6
Gene Alias AMKL; basic SAP and coiled-coil domains; basic SAP coiled-coil transcription activator; basic, SAP and coiled-coil domain; basic, SAP, and coiled-coil domain containing protein; Bsac; FLMKL1; KIAA1438; Mal; megakaryoblastic leukemia (translocation) 1; megakaryoblastic leukemia (translocation) 1 homolog; megakaryoblastic leukemia 1 met; megakaryoblastic leukemia 1 protein; Megakaryoblastic leukemia 1 protein homolog; Megakaryocytic acute leukemia protein; Megakaryocytic acute leukemia protein homolog; MELODY; mixed lineage leukemia; MKL (megakaryoblastic leukemia)/myocardin-like 1; MKL/myocardin-like protein 1; MKL1; MKL1-elongated derivative of yield protein; MKL1met; MRTFA; MRTF-A; myocardin related transcription factor A; myocardin-related transcription factor A
Gene Symbols Mrtfa
Host Species Mouse
Immunogen Recombinant protein fragment of Human MKL1 (Product #RP-91546)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57591
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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