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Invitrogen™ MKL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA599446
Description
Antibody detects endogenous levels of total MKL1.
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
Specifications
MKL1 | |
Polyclonal | |
Unconjugated | |
Mrtfa | |
AMKL; basic SAP and coiled-coil domains; basic SAP coiled-coil transcription activator; basic, SAP and coiled-coil domain; basic, SAP, and coiled-coil domain containing protein; Bsac; FLMKL1; KIAA1438; Mal; megakaryoblastic leukemia (translocation) 1; megakaryoblastic leukemia (translocation) 1 homolog; megakaryoblastic leukemia 1 met; megakaryoblastic leukemia 1 protein; Megakaryoblastic leukemia 1 protein homolog; Megakaryocytic acute leukemia protein; Megakaryocytic acute leukemia protein homolog; MELODY; mixed lineage leukemia; MKL (megakaryoblastic leukemia)/myocardin-like 1; MKL/myocardin-like protein 1; MKL1; MKL1-elongated derivative of yield protein; MKL1met; MRTFA; MRTF-A; myocardin related transcription factor A; myocardin-related transcription factor A | |
Rabbit | |
Affinity Chromatography | |
RUO | |
223701, 315151, 57591 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q8K4J6, Q969V6 | |
Mrtfa | |
A synthesized peptide derived from human MKL1(Accession Q969V6), corresponding to amino acid residues M1-R41. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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