Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA524628

Invitrogen™ MKL2 Monoclonal Antibody (CL1546)
GREENER_CHOICE

Catalog No. PIMA524628
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA524628 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA524628 Supplier Invitrogen™ Supplier No. MA524628
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Immunogen sequence: QRPGPMELVE KNILPVDSSV KEAIIGVGKE DYPHTQGDFS FDEDSSDALS PDQPASQESQ GSAASPSEPK VSESPSPVTT NTPAQFASVS PTVPEFLKTP PTADQPPPRP AAPVLPTNTV SSAKPGPALV KQSHPKNP Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 54%. Binds to an epitope located within the peptide sequence FASVSPTVPEFLKTP as determined by overlapping synthetic peptides.

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factors A and B (MRTF-A and MRTF-B) interact with SRF and act as stimulators for its transcriptional activity. MRTF-B is crucial for skeletal myogenic differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKL2
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CL1546
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mkl2
Gene Accession No. Q9ULH7
Gene Alias CTA-276F8.1; ENSMUSG00000075401; gene trap insertion site 4-1; Gt4-1; KIAA1243; Megakaryoblastic leukemia 2; megakaryoblastic leukemia 2 protein; mKIAA1243; MKL/myocardin like 2; MKL/myocardin-like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; Mkl2; Mrtfb; MRTF-B; myocardin related transcription factor B; myocardin-related transcription factor B; myocardin-related transcription factor B; MKL/myocardin-like protein 2; NPD001; RGD1560833
Gene Symbols Mkl2
Host Species Mouse
Immunogen Recombinant protein fragment of Human MKL2 (Product #RP-89421)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57496
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.