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Invitrogen™ MKL2 Polyclonal Antibody
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Catalog No. PIPA537105
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100 μL
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PIPA537105 100 μL
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Catalog No. PIPA537105 Supplier Invitrogen™ Supplier No. PA537105
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 118 kDa. Purity is >95% by SDS-PAGE.

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factors A and B (MRTF-A and MRTF-B) interact with SRF and act as stimulators for its transcriptional activity. MRTF-B is crucial for skeletal myogenic differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKL2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide
Gene Mkl2
Gene Accession No. P59759, Q9ULH7
Gene Alias CTA-276F8.1; ENSMUSG00000075401; gene trap insertion site 4-1; Gt4-1; KIAA1243; Megakaryoblastic leukemia 2; megakaryoblastic leukemia 2 protein; mKIAA1243; MKL/myocardin like 2; MKL/myocardin-like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; Mkl2; Mrtfb; MRTF-B; myocardin related transcription factor B; myocardin-related transcription factor B; myocardin-related transcription factor B; MKL/myocardin-like protein 2; NPD001; RGD1560833
Gene Symbols Mkl2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues in human MRTF-B.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100362470, 239719, 57496
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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