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Invitrogen™ MKP2 Polyclonal Antibody
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Catalog No. PIPA566440
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100 μL
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PIPA566440 100 μL
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Catalog No. PIPA566440 Supplier Invitrogen™ Supplier No. PA566440
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QVLATSCAAEA ASPSGPLRER GKTPATPTSQ FVFSFPVSVG VHSAPSSLPY LHS Highest antigen sequence identity to the following orthologs - mouse 89%, rat 89%.

DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKP2
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DUSP4
Gene Accession No. Q13115
Gene Alias 2700078F24Rik; AI844617; BB104621; dual specificity phosphatase 4; dual specificity protein phosphatase 4; Dual specificity protein phosphatase hVH2; DUSP 4; DUSP4; DUSP-4; E130306H24Rik; HVH2; MAP kinase phosphatase 2; mitogen-activated protein kinase phosphatase 2; MKP II; Mkp2; Mkp-2; MKPII; serine/threonine specific protein phosphatase; TYP; VH1 homologous phosphatase 2; VH2
Gene Symbols DUSP4
Host Species Rabbit
Immunogen Recombinant Human MKP2. Recombinant protein control fragment (Product #RP-107115).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1846
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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