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Invitrogen™ MKP3 Polyclonal Antibody
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Catalog No. 720405
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100 μg
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Catalog No. Quantity
72-040-5 100 μg
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Catalog No. 72-040-5 Supplier Invitrogen™ Supplier No. 720405
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with Monkey, Dog, Bovine, Horse.

DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Twotranscript variants encoding different isoforms have been found for the DUSP6 gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKP3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
Gene DUSP6
Gene Accession No. Q16828
Gene Alias 1300019I03Rik; dual specificity phosphatase 6; dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; Dusp6; DUSP6-ALT; HH19; MAP kinase phosphatase 3; mitogen-activated protein kinase phosphatase 3; Mkp3; MKP-3; PYST1; serine/threonine specific protein phosphatase
Gene Symbols DUSP6
Host Species Rabbit
Immunogen Peptides corresponding to human MKP3 [1) aa71-aa89 2) aa178-aa195].
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1848
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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