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Invitrogen™ MKP4 Polyclonal Antibody

Catalog No. PIPA528961
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PIPA528961 100 μL
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Catalog No. PIPA528961 Supplier Invitrogen™ Supplier No. PA528961

Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431. Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKP4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene DUSP9
Gene Accession No. Q99956
Gene Alias dual specificity phosphatase 9; dual specificity protein phosphatase 9; dual-specificity MAP kinase phosphatase 4; Dusp4; DUSP9; MAP kinase phosphatase 4; mitogen-activated protein kinase phosphatase 4; MKP4; MKP-4; Mpk4; Pyst3; serine/threonine specific protein phosphatase
Gene Symbols DUSP9
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MKP4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1852
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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