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Tocris Bioscience™ ML 00253764 hydrochloride Available on GSA/VA Contract for Federal Government customers only.

Melanocortin MC4 receptor antagonist; brain penetrant

Manufacturer:  Tocris Bioscience™ 4854/50

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Catalog No. 48-545-0


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Description

Description

Non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 320, 810 and 2120 nM for MC4, MC3 and MC5 receptors respectively). Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor. Increases food intake and reduces loss of lean body mass in tumor bearing mice. Brain penetrant.

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Specifications

Specifications

ML 00253764 hydrochloride
>98
50mg
ML 00253764 hydrochloride
413.71
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