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Tocris Bioscience™ ML 00253764 hydrochloride
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Catalog No. 485450
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Catalog No. Quantity
48-545-0 50 mg
48-541-0 10 mg
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Catalog No. 48-545-0 Supplier Tocris Bioscience™ Supplier No. 4854/50
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Description

Melanocortin MC4 receptor antagonist; brain penetrant

ML 00253764 hydrochloride is a non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 320, 810 and 2120 nM for MC4, MC3 and MC5 receptors respectively). Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor. Increases food intake and reduces loss of lean body mass in tumor bearing mice. Brain penetrant.

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Specifications

Quantity 50 mg
Product Type ML 00253764 hydrochloride
Purity >98%
Molecular Weight (g/mol) 413.71
Inhibitors ML 00253764 hydrochloride

For Research Use Only

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