Tocris Bioscience™ ML 00253764 hydrochloride 

Melanocortin MC4 receptor antagonist; brain penetrant

Manufacturer:  Tocris Bioscience™ 4854/50

Catalog No. 48-545-0

Description

Non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 320, 810 and 2120 nM for MC4, MC3 and MC5 receptors respectively). Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor. Increases food intake and reduces loss of lean body mass in tumor bearing mice. Brain penetrant.

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Specifications

• Product Type: ML 00253764 hydrochloride
• Purity: >98
• Quantity: 50mg

• Inhibitors: ML 00253764 hydrochloride
• Molecular Weight: 413.71

For Research Use Only