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  5. Tocris Bioscience™ ML 120B dihydrochloride

Tocris Bioscience™ ML 120B dihydrochloride
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Catalog No. 489910
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Catalog No. Quantity
48-991-0 10 mg
48-995-0 50 mg
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Catalog No. 48-991-0 Supplier Tocris Bioscience™ Supplier No. 4899/10
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Description

Novel IKK2-selective inhibitor

Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 μM ATP). Exhibits no inhibition at IKK1 (EC50 >100 μM), IKKε (EC50 >100 μM) or a panel of 28 other kinases (EC50 >50 μM). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).

Chemical Identifiers

CAS 783348-36-7
Molecular Formula C19H15ClN4O2

Specifications

Quantity 10 mg
Formula Weight 439.72
Molecular Weight (g/mol) 366.81
Chemical Name or Material ML 120B dihydrochloride

Safety and Handling

Recommended Storage Store at +4°C
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