Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ML 120B dihydrochloride, Tocris Bioscience™

Click to view available options
Quantity:
10mg
50mg
This item is not returnable. View return policy
783348-36-7
C19H15ClN4O2
366.81
ZNOLRTPMNMPLHY-UHFFFAOYSA-N
mln120b,mln-120b,n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methylnicotinamide,ml 120b dihydrochloride,n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methyl-3-pyridinecarboxamide,d0t8is,mln 120b,znolrtpmnmplhy-uhfffaoysa-n,n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methyl-nicotinamide,n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methylnicotinamide
9929127
This item is not returnable. View return policy
783348-36-7
C19H15ClN4O2
366.81
ZNOLRTPMNMPLHY-UHFFFAOYSA-N
mln120b,mln-120b,n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methylnicotinamide,ml 120b dihydrochloride,n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methyl-3-pyridinecarboxamide,d0t8is,mln 120b,znolrtpmnmplhy-uhfffaoysa-n,n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methyl-nicotinamide,n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methylnicotinamide
9929127

Novel IKK2-selective inhibitor

Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 μM ATP). Exhibits no inhibition at IKK1 (EC50 >100 μM), IKKε (EC50 >100 μM) or a panel of 28 other kinases (EC50 >50 μM). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).
Quantity 50mg
Formula Weight 439.72
Chemical Name or Material ML 120B dihydrochloride

Recommended Storage : Store at +4°C