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Tocris Bioscience™ ML 162
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Catalog No. 782110
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Quantity:
10 mg
Catalog No. Quantity
78-211-0 10 mg
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Catalog No. 78-211-0

Supplier: Tocris Bioscience™ 7821/10

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Description

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo. It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).

Specifications

Chemical Name or Material 2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
CAS 1035072-16-2
Quantity 10 mg
Target Glutathione Peroxidase 4/GPX4
Molecular Formula C23H22Cl2N2O3S
Purity 0.98
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