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  5. Tocris Bioscience™ ML 297

Tocris Bioscience™ ML 297
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Catalog No. 538010
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective Kir3.1/3.2 (GIRK1/2) channel activator

ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). Exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters. Prevents PTZ -induced epileptic seizures in mice. Brain penetrant.

Specifications

Quantity 10 mg
Product Type ML 297
Purity >99%
Molecular Weight (g/mol) 328.32
Inhibitors ML 297

For Research Use Only

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