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Tocris Bioscience™ ML 297
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Catalog No. 538010
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53-801-0 10 mg
53-805-0 50 mg
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Catalog No. 53-801-0 Supplier Tocris Bioscience™ Supplier No. 5380/10
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Description

Selective Kir3.1/3.2 (GIRK1/2) channel activator

ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). Exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters. Prevents PTZ -induced epileptic seizures in mice. Brain penetrant.

Specifications

Quantity 10 mg
Product Type ML 297
Purity >99%
Molecular Weight (g/mol) 328.32
Inhibitors ML 297

For Research Use Only

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