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Tocris Bioscience™ ML 339
Potent and selective hCXCR6 antagonist
Supplier: Tocris Bioscience™ 5943/50
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DescriptionML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM). Exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors (IC50 >79 μM).
|N-[(1 R,3 S,5 S)-9-(2-((2-Chlorophenyl)amino)-2-exoethyl)-9-azabicyclo[3.3.1 ]nonan-3-yl)-3,4,5-trimethoxybenzamide|
|Chemokine Receptor Antagonists|
|Soluble to 100mM in DMSO and to 20mM in ethanol|
|Bioactive Small Molecule|
Safety and Handling
Recommended Storage : Store at 4°C
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