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Tocris Bioscience™ ML 347 Available on GSA/VA Contract for Federal Government customers only.

Potent and selective ALK1 and ALK2 inhibitor

Manufacturer:  Tocris Bioscience™ 4945/10

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Catalog No. 49-451-0


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Description

Description

Potent and selective ALK2 and ALK1 inhibitor (IC50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC50 = 152 nM).

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Specifications

Specifications

ML 347
>98
10mg
ML 347
352.39
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