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Tocris Bioscience™ ML 347
Potent and selective ALK1 and ALK2 inhibitor
Supplier: Tocris Bioscience™ 4945/50
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Description
ML 347 is a potent and selective ALK2 and ALK1 inhibitor (IC50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC50 = 152 nM).Specifications
| >98% | |
| 50 mg | |
| 352.39 |
| LDN 193719, 1 lWY, VU0469381 | |
| ML 347 | |
| ML 347 |
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