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  5. Tocris Bioscience™ ML 347

Tocris Bioscience™ ML 347
GREENER_CHOICE

Catalog No. 494550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective ALK1 and ALK2 inhibitor

ML 347 is a potent and selective ALK2 and ALK1 inhibitor (IC50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC50 = 152 nM).

Specifications

Quantity 50 mg
Product Type ML 347
Purity >98%
Molecular Weight (g/mol) 352.39
Inhibitors ML 347

For Research Use Only

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