Invitrogen™ MLC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588797

Catalog No. PIPA588797

Description

Immunogen sequence: SYDVLLLLLL LVLLLQAGLN TGTAIQCVRF KVSARLQGAS WDTQNGPQER LAGEVARSPL KEFDKEKAWR AVVVQMAQ; Positive Samples: SH-SY5Y; Cellular Location: Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane, Multi-pass membrane protein, perinuclear region.

MLC1 may be a transporter. It may act as a non-selective neuronal cation channel.The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: MLC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MLC1
• Gene Alias: AW048630; BB074274; KIAA0027; Kiaa0027-hp; LVM; megalencephalic leukoencephalopathy with subcortical cysts 1; megalencephalic leukoencephalopathy with subcortical cysts 1 gene product; megalencephalic leukoencephalopathy with subcortical cysts 1 homolog; megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human); membrane protein MLC1; mKIAA0027; MLC; MLC1; modulator of VRAC current 1; VL; WKL1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170790, 23209
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.9 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q15049, Q8VHK5
• Gene Symbols: MLC1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human MLC1 (NP_0559811).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG