MLF1 Mouse anti-Human, Clone: OTI3A3, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA504764S

Catalog No. 50-167-5382

Description

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Specifications

• Antigen: MLF1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P58340
• Gene Symbols: MLF1
• Immunogen: Full length human recombit protein of human MLF1 produced in E.coli.
• Quantity: 30 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3A3
• Conjugate: Unconjugated
• Gene: MLF1
• Gene Alias: myeloid leukemia factor 1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4291
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid