MLF1 Mouse anti-Human, Clone: OTI3E7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504827

Catalog No. 50-166-3176

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Specifications

• Antigen: MLF1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MLF1
• Gene Alias: myeloid leukemia factor 1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4291
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI3E7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P58340
• Gene Symbols: MLF1
• Immunogen: Full length human recombit protein of human MLF1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1