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MLF1 Mouse anti-Human, Clone: OTI3E7, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF504827

Encompass_Preferred

Catalog No. 50-166-3176


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Specifications

Specifications

MLF1
Monoclonal
Unconjugated
MLF1
myeloid leukemia factor 1
Mouse
Affinity Chromatography
RUO
4291
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI3E7
PBS with 8% trehalose and no preservative; pH 7.3
P58340
MLF1
Full length human recombit protein of human MLF1 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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