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Invitrogen™ MLK1 Polyclonal Antibody
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Catalog No. PIPA5103309
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100 μL
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PIPA5103309 100 μL
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Catalog No. PIPA5103309 Supplier Invitrogen™ Supplier No. PA5103309
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MAP3K9.

MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLK1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAP3K9
Gene Accession No. P80192, Q3U1V8
Gene Alias E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
Gene Symbols MAP3K9
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAP3K9(Accession P80192), corresponding to amino acid residues D1005-F1055.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 338372, 4293
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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