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Invitrogen™ MLK1 Polyclonal Antibody
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Catalog No. PIPA533917
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50 μg
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Catalog No. Quantity
PIPA533917 50 μg
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Catalog No. PIPA533917 Supplier Invitrogen™ Supplier No. PA533917
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Hamster, Rabbit, Pig (100%).

MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLK1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene MAP3K9
Gene Accession No. P80192, Q3U1V8
Gene Alias E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
Gene Symbols MAP3K9
Host Species Rabbit
Immunogen Synthetic 15 amino acid peptide from internal region of human MAP3K9.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100155753, 100341731, 100762934, 338372, 4293
Target Species Human, Mouse, Rabbit, Hamster, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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